Breton Asken

Breton Asken, Ph.D., ATC

Assistant Professor

Department: Department of Clinical and Health Psychology
Business Phone: (352) 273-9795
Business Email:

About Breton Asken

Breton Asken, PhD, ATC, is an Assistant Professor in the Department of Clinical and Health Psychology at the University of Florida. He is a Fixel Scholar in the Normal Fixel Institute for Neurological Disorders and a member of the Clinical Core of the 1Florida Alzheimer’s Disease Research Center.

Dr. Asken completed bachelors degrees at the University of North Carolina at Chapel Hill (Exercise & Sport Science – Athletic Training, Psychology) and was a research assistant in the Matthew Gfeller Sport-Related Traumatic Brain Injury Research Center. He then earned his doctorate in Clinical Psychology (Neuropsychology track) from the University of Florida and completed his clinical internship in neuropsychology at Brown University. Dr. Asken completed a postdoctoral fellowship in neuropsychology at the UCSF Memory and Aging Center.

Dr. Asken’s research integrates multimodal biomarkers with cognitive and behavioral evaluations to study the complex associations between neuropathological changes and clinical phenotypes among patients with Alzheimer’s disease and related dementias. His sub-focus is studying the role that lifetime head trauma plays later-life neurodegenerative disease, specifically looking at hippocampal and limbic network vulnerability to developing neuropathological changes with aging.

Dr. Asken is an active clinical neuropsychologist in the UF Memory Disorders Clinic and specializes in evaluation of patients with suspected neurodegenerative disease.

Lab Recruitment (updated 4/2024): Dr. Asken currently does not anticipate reviewing graduate student applications for the 2024 Fall/Winter cycle for students planning to enroll in Fall 2025 (subject to change pending funding availability).

Dr. Asken is not currently recruiting postdoctoral fellows but plans to in the future. Prospective fellows should reach out to Dr. Asken to check recruitment status regularly.

Additional Positions:
Fixel Institute Scholar
2022 – ·

Teaching Profile

Courses Taught
CLP6943 Core Practicum in Clinical Psychology
CLP7979 Advanced Research
CLP3911 Introduction to Clinical Research
CLP6971 Research for Master’s Thesis
CLP7980 Research for Doctoral Dissertation
CLP7934 Special Topics In Clinical Psychology

Clinical Profile

Dr. Asken is a clinical neuropsychologist and evaluates patients with a range of cognitive and behavioral conditions at the Fixel Institute for Neurological Diseases in the UF Memory Disorders Clinic. He specializes in neuropsychological evaluation of patients with suspected neurodegenerative diseases like Alzheimer’s disease, as well as less common conditions including primary progressive aphasia, behavioral variant frontotemporal dementia, Lewy body related disorders, corticobasal syndrome, progressive supranuclear palsy, and traumatic encephalopathy syndrome.

Dr. Asken’s clinic works closely with colleagues in behavioral neurology to support multidisciplinary patient care.

  • Psychology

Research Profile

Dr. Asken’s research broadly focuses on clinico-pathological heterogeneity across the spectrum of Alzheimer’s disease and related dementias (ADRDs). He has specific interests in how lifetime head trauma exposure relates to clinical and neuropathological variability among patients with ADRD, including chronic traumatic encephalopathy (CTE). This work involves using a combination of neuropsychological testing, fluid-based biomarkers (blood, CSF), neuroimaging, and neuropathology to address the links between head trauma and dementia. Dr. Asken is especially interested in how biomarkers and cognitive testing can help improve diagnosis, prognosis, and treatment of mixed etiology dementia, or progressive cognitive/behavioral decline in later life due to multiple co-existing neurodegenerative diseases. Prior work focused on fluid biomarkers and recovery outcomes associated with sport-related concussion, and this experience relates directly to his current interests in the later-life neurological effects of head trauma exposure, especially among former athletes. Dr. Asken has active collaborations with investigators across UF as well as multiple institutions around the country.

Individuals interested in Dr. Asken’s research lab may have diverse goals and experiences. While an ideal “fit” is someone pursuing a clinical-research career in neuropsychology and hoping to study how head trauma exposure relates to later-life neurological conditions like dementia, Dr. Asken welcomes a broad range of interests within the field of aging/Alzheimer’s disease and related causes of dementia. At a bare minimum, Dr. Asken’s expectation as a research mentor is that trainees will leave their experience excited to apply the knowledge gained about neurodegenerative syndromes and the brain changes that can cause them to their own research, clinical work, or both.

Open Researcher and Contributor ID (ORCID)


Areas of Interest
  • Alzheimer’s Disease
  • Biomarkers
  • Brain Injury
  • Chronic Traumatic Encephalopathy
  • Clinico-Pathology of Neurodegenerative Disease
  • Dementia
  • Memory and cognitive disorders
  • Neurodegenerative diseases of aging
  • Neuropsychology
  • Sports
  • TDP-43 proteinopathies


Different aspects of failing to recover from proactive semantic interference predicts rate of progression from amnestic mild cognitive impairment to dementia.
Frontiers in aging neuroscience. 16 [DOI] 10.3389/fnagi.2024.1336008. [PMID] 38357533.
Linking Type and Extent of Head Trauma to Cavum Septum Pellucidum in Older Adults With and Without Alzheimer Disease and Related Dementias
Neurology. 102(7) [DOI] 10.1212/wnl.0000000000209183.
Plasma Alzheimer’s biomarkers and brain amyloid in Hispanic and non-Hispanic older adults.
Alzheimer's & dementia : the journal of the Alzheimer's Association. 20(1):437-446 [DOI] 10.1002/alz.13456. [PMID] 37671801.
Plasma phosphorylated tau-217 exhibits sex-specific prognostication of cognitive decline and brain atrophy in cognitively unimpaired adults.
Alzheimer's & dementia : the journal of the Alzheimer's Association. 20(1):376-387 [DOI] 10.1002/alz.13454. [PMID] 37639492.
Alzheimer’s pathology is associated with altered cognition, brain volume, and plasma biomarker patterns in traumatic encephalopathy syndrome.
Alzheimer's research & therapy. 15(1) [DOI] 10.1186/s13195-023-01275-w. [PMID] 37480088.
Evaluation of Plasma Phosphorylated Tau217 for Differentiation Between Alzheimer Disease and Frontotemporal Lobar Degeneration Subtypes Among Patients With Corticobasal Syndrome.
JAMA neurology. 80(5):495-505 [DOI] 10.1001/jamaneurol.2023.0488. [PMID] 37010841.
Plasma inflammation for predicting phenotypic conversion and clinical progression of autosomal dominant frontotemporal lobar degeneration
Journal of Neurology, Neurosurgery & Psychiatry. 94(7):541-549 [DOI] 10.1136/jnnp-2022-330866. [PMID] 36977552.
Predicting Progression to Clinical Alzheimer’s Disease Dementia Using the Random Survival Forest.
Journal of Alzheimer's disease : JAD. 95(2):535-548 [DOI] 10.3233/JAD-230208. [PMID] 37545237.
Amyloid, tau and metabolic PET correlates of cognition in early and late-onset Alzheimer’s disease.
Brain : a journal of neurology. 145(12):4489-4505 [DOI] 10.1093/brain/awac229. [PMID] 35762829.
Blood pressure characteristics of collegiate female athletes: A call for more focused attention on young women’s health.
American heart journal plus : cardiology research and practice. 13 [DOI] 10.1016/j.ahjo.2022.100085. [PMID] 38560086.
Hepatic and renal function impact concentrations of plasma biomarkers of neuropathology.
Alzheimer's & dementia (Amsterdam, Netherlands). 14(1) [DOI] 10.1002/dad2.12321. [PMID] 35845260.
Lower White Matter Volume and Worse Executive Functioning Reflected in Higher Levels of Plasma GFAP among Older Adults with and Without Cognitive Impairment.
Journal of the International Neuropsychological Society : JINS. 28(6):588-599 [DOI] 10.1017/S1355617721000813.
Multi-Modal Biomarkers of Repetitive Head Impacts and Traumatic Encephalopathy Syndrome: A Clinicopathological Case Series.
Journal of neurotrauma. [DOI] 10.1089/neu.2022.0060. [PMID] 35481808.
Plasma P-tau181 and P-tau217 in Patients With Traumatic Encephalopathy Syndrome With and Without Evidence of Alzheimer Disease Pathology.
Neurology. [DOI] 10.1212/WNL.0000000000200678. [PMID] 35577574.
Retinal arteriolar parameters as a surrogate marker of intracranial vascular pathology.
Alzheimer's & dementia (Amsterdam, Netherlands). 14(1) [DOI] 10.1002/dad2.12338. [PMID] 35814617.
Association of remote mild traumatic brain injury with cortical amyloid burden in clinically normal older adults
Brain Imaging and Behavior. 15(5):2417-2425 [DOI] 10.1007/s11682-020-00440-1. [PMID] 33432536.
Development and validation of the Uniform Data Set (v3.0) executive function composite score (UDS3-EF).
Alzheimer's & dementia : the journal of the Alzheimer's Association. 17(4):574-583 [DOI] 10.1002/alz.12214. [PMID] 33215852.
Genetic pleiotropy and the shared pathological features of corticobasal degeneration and progressive supranuclear palsy: a case report and a review of the literature.
Neurocase. 27(2):120-128 [DOI] 10.1080/13554794.2021.1879869. [PMID] 33754963.
Identifying degenerative effects of repetitive head trauma with neuroimaging: a clinically-oriented review.
Acta neuropathologica communications. 9(1) [DOI] 10.1186/s40478-021-01197-4. [PMID] 34022959.
Making a Difference: Affective Distress Explains Discrepancy Between Objective and Subjective Cognitive Functioning After Mild Traumatic Brain Injury.
The Journal of head trauma rehabilitation. 36(3):186-195 [DOI] 10.1097/HTR.0000000000000618. [PMID] 32898033.
Plasma Glial Fibrillary Acidic Protein Levels Differ Along the Spectra of Amyloid Burden and Clinical Disease Stage.
Journal of Alzheimer's disease : JAD. 80(1):471-474 [DOI] 10.3233/JAD-219001. [PMID] 33612550.
Professional Soccer and Dementia Risk-The Ugly Side of the Beautiful Game.
JAMA neurology. 78(9):1049-1051 [DOI] 10.1001/jamaneurol.2021.2246. [PMID] 34338741.
Acute Effects of Sport-Related Concussion on Serum Glial Fibrillary Acidic Protein, Ubiquitin C-Terminal Hydrolase L1, Total Tau, and Neurofilament Light Measured by a Multiplex Assay.
Journal of neurotrauma. 37(13):1537-1545 [DOI] 10.1089/neu.2019.6831. [PMID] 32024456.
Discrepancy-Based Evidence for Loss of Thinking Abilities (DELTA): Development and Validation of a Novel Approach to Identifying Cognitive Changes
Journal of the International Neuropsychological Society. 26(5):464-479 [DOI] 10.1017/s1355617719001346.
King-Devick Test Time Varies by Testing Modality.
Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine. 30(5):e139-e142 [DOI] 10.1097/JSM.0000000000000691. [PMID] 30358616.
Sex-related differences in the relationship between β-amyloid and cognitive trajectories in older adults.
Neuropsychology. 34(8):835-850 [DOI] 10.1037/neu0000696. [PMID] 33030915.
Word-reading ability as a “hold test” in cognitively normal young adults with history of concussion and repetitive head impact exposure: A CARE Consortium Study
The Clinical Neuropsychologist. 34(5):919-936 [DOI] 10.1080/13854046.2019.1680735.
Author response: Concussion Biomarkers Assessed in Collegiate Student-Athletes (BASICS) I: Normative study.
Neurology. 93(12) [DOI] 10.1212/WNL.0000000000008144. [PMID] 31527106.
Concussion Biomarkers: Deviating From the Garden Path.
JAMA neurology. 76(5):515-516 [DOI] 10.1001/jamaneurol.2019.0125. [PMID] 30830175.
Drill-Specific Head Impacts in Collegiate Football Practice: Implications for Reducing “Friendly Fire” Exposure.
Annals of biomedical engineering. 47(10):2094-2108 [DOI] 10.1007/s10439-018-2088-5. [PMID] 29987539.
Echocardiographic measurements of aortic root diameter (ARD) in collegiate football Athletes at pre-participation evaluation.
BMJ open sport & exercise medicine. 5(1) [DOI] 10.1136/bmjsem-2019-000546. [PMID] 31258930.
Echocardiographic measurements of left ventricular end-diastolic diameter and interventricular septal diameter in collegiate football athletes at preparticipation evaluation referenced to body surface area.
BMJ open sport & exercise medicine. 5(1) [DOI] 10.1136/bmjsem-2018-000488. [PMID] 31205743.
Exploratory study of sport-related concussion effects on peripheral micro-RNA expression
Brain Injury. 33(4):1-7 [DOI] 10.1080/02699052.2019.1573379. [PMID] 30704304.
Multivariate Base Rates of Low Scores and Reliable Decline on ImPACT in Healthy Collegiate Athletes Using CARE Consortium Norms.
Journal of the International Neuropsychological Society : JINS. 25(9):961-971 [DOI] 10.1017/S1355617719000729. [PMID] 31272517.
Predicting long-term cognitive and neuropathological consequences of moderate to severe traumatic brain injury: Review and theoretical framework.
Journal of clinical and experimental neuropsychology. 41(8):775-785 [DOI] 10.1080/13803395.2019.1620695. [PMID] 31156042.
Relationship Between the King-Devick Test and Commonly Used Concussion Tests at Baseline.
Journal of athletic training. 54(12):1247-1253 [DOI] 10.4085/1062-6050-455-18. [PMID] 31584854.
Chronic Traumatic Encephalopathy: The Horse Is Still Chasing the Cart.
The Journal of orthopaedic and sports physical therapy. 48(9):672-675 [DOI] 10.2519/jospt.2018.0612. [PMID] 30170520.
Concussion BASICS II: Baseline serum biomarkers, head impact exposure, and clinical measures.
Neurology. 91(23):e2123-e2132 [DOI] 10.1212/WNL.0000000000006616. [PMID] 30404782.
Concussion BASICS III: Serum biomarker changes following sport-related concussion.
Neurology. 91(23):e2133-e2143 [DOI] 10.1212/WNL.0000000000006617. [PMID] 30404786.
Concussion Biomarkers Assessed in Collegiate Student-Athletes (BASICS) I: Normative study.
Neurology. 91(23):e2109-e2122 [DOI] 10.1212/WNL.0000000000006613. [PMID] 30404785.
Diffusion tensor imaging (DTI) findings in adult civilian, military, and sport-related mild traumatic brain injury (mTBI): a systematic critical review.
Brain imaging and behavior. 12(2):585-612 [DOI] 10.1007/s11682-017-9708-9. [PMID] 28337734.
Glymphatic system disruption as a mediator of brain trauma and chronic traumatic encephalopathy.
Neuroscience and biobehavioral reviews. 84:316-324 [DOI] 10.1016/j.neubiorev.2017.08.016. [PMID] 28859995.
Immediate Removal From Activity After Sport-Related Concussion Is Associated With Shorter Clinical Recovery and Less Severe Symptoms in Collegiate Student-Athletes.
The American journal of sports medicine. 46(6):1465-1474 [DOI] 10.1177/0363546518757984. [PMID] 29558195.
Isolated “Low” Test Scores Are Often Normal and Valid.
Medicine and science in sports and exercise. 50(10) [DOI] 10.1249/MSS.0000000000001664. [PMID] 30216267.
Socioeconomic Status and Race Outperform Concussion History and Sport Participation in Predicting Collegiate Athlete Baseline Neurocognitive Scores.
Journal of the International Neuropsychological Society : JINS. 24(1):1-10 [DOI] 10.1017/S1355617717000716. [PMID] 28791942.
Tau in Chronic Traumatic Encephalopathy-Reply.
JAMA neurology. 75(3):381-382 [DOI] 10.1001/jamaneurol.2017.4893. [PMID] 29404562.
The modern landscape of sport-related concussion research: key achievements and future directions.
Handbook of clinical neurology. 158:269-278 [DOI] 10.1016/B978-0-444-63954-7.00026-4. [PMID] 30482355.
Baseline Neurocognitive Performance and Clearance for Athletes to Return to Contact.
Journal of athletic training. 52(1):51-57 [DOI] 10.4085/1062-6050-51.12.27. [PMID] 27905859.
Concussion-like symptom reporting in non-concussed adolescent athletes.
The Clinical neuropsychologist. 31(1):138-153 [DOI] 10.1080/13854046.2016.1246672. [PMID] 27758158.
Concussion-Like Symptom Reporting in Non-Concussed Collegiate Athletes
Archives of Clinical Neuropsychology. 32(8):963-971 [DOI] 10.1093/arclin/acx018.
Descriptive Characteristics of Concussions in National Football League Games, 2010-2011 to 2013-2014.
The American journal of sports medicine. 45(4):929-936 [DOI] 10.1177/0363546516677793. [PMID] 28056179.
Injury cascades in TBI-related neurodegeneration
Brain Injury. 31(9):1177-1182 [DOI] 10.1080/02699052.2017.1312528. [PMID] 28981345.
Neuropsychological Screening of Sport-Related Concussion.
Neurologic clinics. 35(3):487-500 [DOI] 10.1016/j.ncl.2017.03.005. [PMID] 28673411.
Research Gaps and Controversies in Chronic Traumatic Encephalopathy: A Review.
JAMA neurology. 74(10):1255-1262 [DOI] 10.1001/jamaneurol.2017.2396. [PMID] 28975240.
“Playing Through It”: Delayed Reporting and Removal From Athletic Activity After Concussion Predicts Prolonged Recovery.
Journal of athletic training. 51(4):329-35 [DOI] 10.4085/1062-6050-51.5.02. [PMID] 27111584.
Epidemiology of Sport-Related Concussion in an NCAA Division I Football Bowl Subdivision Sample.
The American journal of sports medicine. 44(9):2269-75 [DOI] 10.1177/0363546516645070. [PMID] 27159307.
Factors Influencing Clinical Correlates of Chronic Traumatic Encephalopathy (CTE): a Review.
Neuropsychology review. 26(4):340-363 [PMID] 27561662.


Jun 2020 ACTIVE
1Florida Alzheimers Disease Research Center
Role: Project Manager


Postdoctoral Neuropsychology Fellowship
2019-2022 · UCSF Memory and Aging Center
Clinical Psychology (Neuropsychology) Internship
2018-2019 · Brown University
Clinical Psychology (PhD)
2013-2019 · University of Florida
Exercise & Sport Science – Athletic Training (BA)
2009-2013 · University of North Carolina at Chapel Hill
Psychology (BA)
2009-2013 · University of North Carolina at Chapel Hill

Contact Details

(352) 273-9795
Business Street: