Adam J Woods

Adam J Woods, Ph.D.

Associate Professor, Assistant Program Director

Department: HP-CLINICAL / HLTH PSYCHOLOGY
Business Phone: (352) 294-5842
Business Email: ajwoods@phhp.ufl.edu

About Adam J Woods

Dr. Woods is Associate Director of the Center for Cognitive Aging and Memory (CAM) in the McKnight Brain Institute at UF. Dr. Woods is also an Associate Professor in the Department of Clinical and Health Psychology at UF, with a joint appointment to Neuroscience. Dr. Woods completed a post-doctoral fellowship in Cognitive Neuroscience at the University of Pennsylvania after completing his PhD in Cognitive Neuroscience at George Washington University. His undergraduate training in Psychology was completed at the University of Alabama at Birmingham. He has expertise in non-invasive brain stimulation, neuroimaging, and cognitive training for working memory and speed of processing/attention. He is a national leader in the field of neuromodulation, leading the largest transcranial electrical stimulation (tES) and near infrared photobiomodulation trials to date, multiple cognitive training trials, publishing the first comprehensive textbook in the field of tES, and multiple field standards papers. Dr. Woods’ research specifically focuses on discovery and application of novel non-invasive interventions for enhancing cognitive function in adults with and without neurodegenerative disease. Dr. Woods has expertise in multi-disciplinary cognitive neuroscience methodologies (MRI/fMRI, electrophysiology, non-invasive brain stimulation), extensive experience with aging-related cognitive disorders, cognitive training applications, and past research with neurological diseases. Over the past five years, Dr. Woods has established one of the largest and most well-funded neuromodulation laboratories in the United States. He is PI of the first and largest phase III RCT for tES using transcranial direct current stimulation (tDCS) and cognitive training, the ACT study (R01AG054077, n=360), the largest phase II near infrared photobiomodulation trial (R01AG064587, n=168), one of the largest phase II tES trials, the Stimulated Brain Study (K01AG054077, n=80), as well as an R21 and U01 investigating the effects of neuromodulation on the aging brain (R21MH112206, U01AG062368). He also serves as co-I on multiple other NIH funded grants focused on neuromodulation of cognitive aging, chronic pain, and mobility using transcranial electrical stimulation (RF1MH114290, R37AG033906, R21AG053736). Each of these studies attempts to enhance cognitive and brain function in older adults and prevent dementia through neuromodulation.

Honors & Awards

2019 · University of Florida
2018-2020 · University of Florida
2016-2021 · National Institute on Aging
2015-2019 · National Institute on Aging
2015 · NYC Neuromodulation Conference 2015
2014 · University of Florida Clinical Translational Science Institute
2009-2010 · George Washington University
2006-2009 · National Science Foundation
2003 · University of Alabama at Birmingham Department of Psychology

Research Profile

Cognitive Aging and Dementia: Cognitive function declines as we age. As our thinking and memory skills decline, the rate of functional dependence, mortality, and acute illness requiring hospitalization increases. Increased rates of cognitive and functional decline associated with dementia represent a growing concern in light of our rapidly aging population. There are currently a paucity of effective treatments for preventing dementia or recovering age-related cognitive decline. A variety of methods have been proposed to counteract cognitive aging and/or slow onset of dementia (e.g., cognitive training). Unfortunately, these techniques have limited degrees of success and transfer to everyday life. My work demonstrates that combining treatments like cognitive training with non-invasive brain stimulation (tDCS, TMS, tACS) facilitates neural plastic response, improves cognitive abilities (specifically working memory, attention, and speed of processing), and leads to long-term improvement. In combination with modern multimodal neuroimaging and electrophysiology recording, this work not only identifies mechanisms underlying improvement, but also provides information important for further optimizing treatment effectiveness. This work has recently led to funding of the largest and only Phase III randomized clinical trial for tDCS as an adjunctive method with cognitive training to combat cognitive aging and slow dementia onset. In addition, my lab is funded to investigate mobility enhancement in older adults, treat chronic knee osteoarthritic pain, and enhance working memory using a variety of non-invasive electrical brain stimulation methods in Phase II trials. At present, my lab maintains over 7 million dollars in NIH funding to investigate non-invasive brain stimulation-related interventions. In addition, my lab also maintains funding to investigate a variety of non-pharmacological compounds in a Phase II pilot clinical trials to investigate novel methods for improving brain metabolism, neuroplasticity, and cognitive function. This work capitalizes on novel methods for imaging mitochondrial function and cerebral energy metabolism in the brain, as well as state of the art diffusion-weighted and functional imaging methods. Collectively, my work aims to slow or reverse the effects of cognitive aging and slow the onset of dementia using non-invasive and minimally invasive approaches. In addition, the extension of my work to chronic pain and mobility decline in older adults represents an exciting new arm of my intervention work.

Areas of Interest
  • Alzheimer’s Disease
  • Attention
  • Clinical Translational Neuroscience
  • Cognitive Aging
  • Cognitive Neuroscience
  • Dementia
  • MR imaging
  • Neuroimaging Methods
  • Neuromodulation
  • Neuroplasticity
  • Non-invasive Brain Stimulation
  • Speed of Processing
  • Working Memory

Publications

2019 Frontiers in Psychology
2019 Alcoholism: Clinical and Experimental Research
2018 Alcoholism, clinical and experimental research
2017 Biological psychiatry. Cognitive neuroscience and neuroimaging
2017 Geriatrics & Gerontology International
2016 Frontiers in Aging Neuroscience
2013 Acta psychologica (Online)
2013 Journal of Nutrition Health & Aging
2011 PM & R : the journal of injury, function, and rehabilitation
2009 Journal of Experimental Psychology-Human Perception and Performance
2008 Attention Perception and Psychophysics
2007 Journal of Clinical and Experimental Neuropsychology
2005 Archives of Physical Medicine and Rehabilitation

Grants

Sep 2019 ACTIVE
IPA for Adam Woods
US DEPT OF VET AFF GAINESVILLE MED CTR · Principal Investigator
Aug 2019 ACTIVE
Revitalizing Cognition in Older Adults at Risk for Alzheimer's Disease with Near-Infrared Photobiomodulation.
NATL INST OF HLTH NIA ·
Jun 2019 ACTIVE
Ethnic Differences in Responses to Painful Stimuli
NATL INST OF HLTH NIA ·
Jun 2019 ACTIVE
Revitalizing Cognition and Motor Symptoms in Parkinson Disease: A Pilot Intervention with Near Infrared Stimulation
PARKINSONS FOU ·
Sep 2018 – May 2020
Planning an Adaptive Clinical Trial of Cognitive Training to Improve Function and Delay Dementia
UNIV OF SOUTH FLORIDA · Principal Investigator
Sep 2018 – May 2020
Role of Gut Microbial Dysbiosis and Aging on HIV-associated Neurocognitive and Brain Dysfunction
UNIVERSITY OF LOUISVILLE RES FOU · Project Manager
May 2018 ACTIVE
A Pilot Intervention with Near Infrared Stimulation: Revitalizing Cognition in Older Adults
MCKNIGHT BRAIN RESEARCH FOU ·
Jan 2018 ACTIVE
Stimulating Theta Oscillations to Enhance Working Memory
NATL INST OF HLTH NIMH ·
Jul 2017 ACTIVE
Mechanism and dosimetry exploration in transcranial electrical stimulation using magnetic resonance current mapping methods
ARIZONA STATE UNIVERSITY · Project Manager
Jun 2017 – May 2020
Combining tDCS and neurorehabilitation to treat age-related deficits of mobility and cognition
NATL INST OF HLTH NIA ·
Sep 2016 ACTIVE
Neuromodulation of Cognition in Older Adults
NATL INST OF HLTH NIA · Principal Investigator
Sep 2016 ACTIVE
Effects of experimentally-induced reductions in alcohol consumption on brain cognitive, and clinical outcomes and motivation for changing drinking in older persons with HIV infection
NATL INST OF HLTH NIAAA ·
Sep 2016 ACTIVE
Augmenting Cognitive Training in Older Adults – The ACT Grant
NATL INST OF HLTH NIA · Principal Investigator
Jun 2016 – Jun 2018
The influence of Fermented Papaya Preparation (FPP) on cerebral energy metabolism, neuroinflammation, and cognition in older adults (The Efficient Brain Study)
OSATO RESEARCH INSTITUTE · Principal Investigator
Apr 2016 ACTIVE
NEUROMODULATION OF COGNITIVE FUNCTION USING TRANSCRANIALDIRECT CURRENT STIMULATION
UF FOU · Principal Investigator
Feb 2016 – Jan 2018
pilot intervention in mild cognitive impairment:
FL DEPT OF HLTH ED ETHEL MOORE ALZHEIMER · Project Manager
Sep 2015 – May 2020
Alcohol and HIV: Biobehavioral Interactions and Interventions
BROWN UNIV ·
May 2015 – Mar 2016
Together: Transforming and Translating Discovery to
NATL INST OF HLTH NCATS · Project Manager
Jul 2014 ACTIVE
Age associated changes in attention and arousal (Attentive Brain Study)
UF FOU · Project Manager
Jul 2014 ACTIVE
Aging effects on semantic neural networks (Talking Brain Study)
UF FOU · Principal Investigator
Jul 2014 ACTIVE
Aging effects on visual cortical systems (seeing Brain Study)
UF FOU · Principal Investigator
Jul 2014 ACTIVE
The Impact of urinary tract infection on cognitive function in older adults
UF FOU · Principal Investigator
Jun 2014 – Dec 2018
Neuromodulation of cognition in older adults
UF FOU · Principal Investigator
Jan 2014 ACTIVE
the ACTIVE BRAIN study- cerebral metabolic, vascular
UF FOU · Principal Investigator

Education

Ph.D. Cognitive Neuroscience
2005-2010 · George Washington University
B.S.
1999-2003 · University of Alabama at Birmingham

Contact Details

Phones:
Business:
(352) 294-5842
Emails:
Addresses:
Mailing:
PO Box 100165
GAINESVILLE FL 32610