Cheshire Hardcastle, M.S.

Cheshire HardcastleBiography

Cheshire Hardcastle is a graduate student at the University of Florida in the Department of Clinical and Health Psychology. Cheshire graduated Summa cum laude from the University of Cincinnati in 2013 with a B.A. in psychology. Cheshire then worked at the Stanford Research Institution (SRI) researching alcoholism and HIV. Cheshire then earned her Master’s in Neuroimaging for Clinical and Cognitive Neuroscience from the University of Manchester in Manchester, England. Her thesis involved researching certain imaging methods to measure cerebral blood perfusion in an elderly population. Cheshire is currently in the neuropsychology track, where she works under the membership of Dr. Catherine Price.

Research Focus

Cheshire’s current research focuses on using neuroimaging and behavioral assessment methods to better understand Post Operative Cognitive Decline (POCD). She is specifically exploring changes in white matter integrity after surgery, and how this may affect cognitive processes like attention and memory.


Hardcastle, V.G., and Hardcastle, C. (2015). Addiction, Freedom, and Responsibility. American Journal of Bioethics-Neuroscience, 6(2): 19-21.

Hardcastle, V.G., and Hardcastle, C.  (2016) Addiction, Chronic Illness, and Responsibility. Ideas y Valores.

Hardcastle, C., White, E., Kloos, H., and Hardcastle, V.G. (2016) Heavy Objects and Small Children: Developmental Data in Support of Passive Frame Theory. Behavioral and Brain Sciences. 39.

Fama, R., Le Berre, A.P, Hardcastle, C., Sassoon, S. A., Zahr, N. M., Pfefferbaum, A., Sullivan, E.V. (2017) Neurological, nutritional, and alcohol consumption factors underlie cognitive and motor deficits in chronic alcoholism.  Addiction Biology (in press).

Sassoon, S. A., Le Berre, A.P., Fama, R., Asok, P., Hardcastle, C., Chu, W., Pfefferbaum, A., Sullivan, E. (2017) Effects of childhood trauma and alcoholism history on neuropsychological performance in adults with HIV infection: an initial study. Journal of HIV/AIDS and Infectious Diseases. 3(101).


Jacola L.M., Hardcastle C., Shear P.K., Lisdahl K., Howe S.R., Esbensen A., Hickey F. (2012). Measures of maladaptive behavior in adolescents with Down syndrome. Association for Psychological Science, Chicago, IL.

Hardcastle, C., Barnes, J., Haralson, K., Shenk, C., Simmons, K., Powers, A., Noll, J. (2012). Teen Risk Variables Associated with High-risk Internet Behaviors: The Impact on Subsequent Offline Meetings and the Mediating Role of Parents. Society for Research on Adolescents. Bienniel meeting, Vancouver, Canada.

Hardcastle, C., Marlatt, E., Bennet, M., and Sarkoc, J. (2012). Judging Affordance by Hefting in Preschooolers.  Undergraduate Research Expo, University of Cincinnati.

Hardcastle, C., Hardcastle, V.G. (2014). Brain scans in the Courtroom: Cautions, Challenges, and Concerns. International Neuroethics Society Annual Meeting. Washington, D.C.

Fama, R., Sassoon, S.A., Hardcastle, C., Rohlfing, T., Sullivan, E., Pfefferbaum, A. (2015). Temporo-parietal contribution to visual episodic memory performance in HIV infection. International Neuropsychology Society Annual Meeting. Denver, CO.

Collins, A. M., Hardcastle, C., Zahr, N. M., Sullivan, E.V., Pfefferbaum, A. (2015). In vivo imaging evidence for variable CNS responses to repeated binge ethanol treatment. Annual SRI Biosciences Poster Day. Menlo Park, CA

Hardcastle, C., Hardcastle, V. (2015). Addiction, maladaptive behavior, and responsibility. International Neuroethics Society Annual Meeting, Chicago, Illinois.

Hardcastle, C., and Hardcastle, V.G. (2015) Brain plasticity, neuroimaging, and the courtroom. American Society for Bioethics and Humanities Annual Meeting, Houston, TX.

Peterson, E., Zahr, N. M., Serventi, M., Hardcastle, C., Sullivan, E.V., Pfefferbaum, A. (2016). Intra voxel incoherent motion in the brain: a repeatability and aging study. Abstract no. 1094. Proceedings of the International Society of Magnetic Resonance in Medicine Annual Conference, Singapore.

Muller-Oehring, E.M., Poston, K.M., Bronte-Stewart, H., Hardcastle, C., Martin, T., Pfefferbaum, A., Sullivan, E.V., Schulte, T. (2016) Aging with HIV infection – neurofunctional response to cognitive interference and motor demands: a comparison with Parkinson’s Disease. Society for Neuroscience, San Diego, California.

Sassoon, S.A., Le Berre, A.P., Fama, R., Asok, P., Hardcastle, C., Chu, W., Bonilla, A., Pfefferbaum, A., Sullivan, E.V. (2016) Relation between early childhood trauma and cognitive and motor performance in HIV-infected adults with and without alcoholism. Research Society on Alcoholism, New Orleans, LA.

Fama, R., Hardcastle, C., Sassoon, S., Zahr, N., Pfefferbaum, A., Sullivan, E. (2016) Neurological and nutritional biomarkers of cognitive impairment in alcoholics. International Neuropsychological Society, New Orleans, LA.

Hardcastle, C., Hendershott, T.R., Fama R., Muller-Oehring, E.M., Sullivan, E.V., Pfeffermaum, A., Poston, K.L., Bronte-Stewart, H.M., Schulte, T. (forthcoming, 2017) Cognitive and motor functioning in older adults with HIV: A comparison with Parkinson’s disease. International Neuropsychological Society, New Orleans, LA.

Honors and Awards


University Honors Program University of Cincinnati 2011
Summer Undergraduate Research Fellowship University of Cincinnati Medical Caenter 2011
Doris Twitchell Allen Award for Outstanding Senior Woman in Psychology University of Cincinnati 2013
College Marshal University of Cincinnati 2013
Graduation Summa Cum Laude University of Cincinnati 2013
North American Fellowship for the University of Manchester (NAFUM) 2016
Grinter Fellowship  University of Florida 2017